Chapter 3
USMLE Step 1 – Inflammation & Healing Quiz
1. A 45-year-old man presents with fever, productive cough, and right-sided chest pain. Chest X-ray shows consolidation of the right lower lobe. Sputum culture grows Streptococcus pneumoniae. Which of the following best describes the type of inflammatory exudate expected in this condition?
2. A 7-year-old boy has recurrent bacterial infections involving the skin, lungs, and lymph nodes. Laboratory studies show normal neutrophil count but impaired respiratory burst. Nitroblue tetrazolium test is negative. Which of the following is the most likely diagnosis?
3. A 35-year-old woman undergoes excision of a benign breast mass. Six months later, she develops a raised, firm scar that extends beyond the boundaries of the original surgical incision. The lesion is pruritic and does not regress over time. Which of the following best describes this lesion?
4. A 60-year-old man with a 30-year history of smoking presents with hemoptysis. Bronchoscopy reveals a mass in the right main bronchus. Biopsy shows squamous cell carcinoma. Microscopic examination of the tumor stroma reveals numerous fibroblasts and dense collagen deposition. Which of the following terms best describes this stromal reaction?
5. A 25-year-old woman presents with fever, weight loss, and chronic diarrhea. Colonoscopy shows segmental areas of inflammation with deep, linear ulcers. Biopsy reveals transmural inflammation with non-caseating granulomas. Which of the following is the most likely diagnosis?